Limestone County, Alabama is home to Pryor Field Regional Airport, one of the busiest general aviation airports in the state. Pryor Field Regional Airport features a 6,107-foot lighted, instrument-landing equipped runway. Huntsville International Airport is located on the border of Limestone County.
The International Intermodal Center is on the border of Limestone County at the Port of Huntsville, giving area industries the ability to ship and receive goods internationally.
The Port of Decatur is located within 15 minutes of Limestone County, giving access to the Tennessee River and the Tennessee-Tombigbee Waterway.